Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice

Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice

Objective: Knee osteoarthritis (KOA) is a highly prevalent musculoskeletal disorder characterized by degeneration of cartilage and abnormal remodeling of subchondral bone (SCB). Teriparatide (PTH (1–34)) is an effective anabolic drug for osteoporosis (OP) and regulates osteoprotegerin (OPG)/receptor...

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Bibliographic Details
Main Authors: Guoqing Li, Su Liu, Yixiao Chen, Huihui Xu, Tiantian Qi, Ao Xiong, Deli Wang, Fei Yu, Jian Weng, Hui Zeng
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Teriparatide (PTH (1–34))
Knee osteoarthritis
Cartilage
Subchondral bone
Osteoprotegerin (OPG)
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X22001279

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http://www.sciencedirect.com/science/article/pii/S2214031X22001279

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