SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis

SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis

Angiogenesis is a significant pathogenic characteristic of diabetic microangiopathy. Advanced glycation end products (AGEs) are considerably elevated in diabetic tissues and can affect vascular endothelial cell shape and function. Regulation of the vascular endothelial growth factor (VEGF)-VEGF rece...

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Bibliographic Details
Main Authors: Qi He, Zhenfeng Chen, Jieyu Li, Jinlian Liu, Zirui Zuo, Bingqi Lin, Ke Song, Chuyu Zhou, Haipeng Lai, Qiaobing Huang, Xiaohua Guo
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
advanced glycation end products (AGEs)
VEGFR2
SUMOylation
SENP6
angiogenesis
Online Access:https://www.mdpi.com/1422-0067/24/3/2544

Internet

https://www.mdpi.com/1422-0067/24/3/2544

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