CD8+ T cell trajectory subtypes decode tumor heterogeneity and provide treatment recommendations for hepatocellular carcinoma

CD8+ T cell trajectory subtypes decode tumor heterogeneity and provide treatment recommendations for hepatocellular carcinoma

IntroductionMounting evidence has revealed that the interactions and dynamic alterations among immune cells are critical in shaping the tumor microenvironment and ultimately map onto heterogeneous clinical outcomes. Currently, the underlying clinical significance of immune cell evolutions remains la...

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Bibliographic Details
Main Authors: Long Liu, Zaoqu Liu, Jie Gao, Xudong Liu, Siyuan Weng, Chunguang Guo, Bowen Hu, Zhihui Wang, Jiakai Zhang, Jihua Shi, Wenzhi Guo, Shuijun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
hepatocellular carcinoma
single-cell RNA-seq
immunotherapy
heterogeneity
prognosis
clinical treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.964190/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.964190/full

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