Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit

Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit

CD133 (prominin 1) is widely viewed as a cancer stem cell marker in association with drug resistance and cancer recurrence. Herein, we report that with impaired RTK-Shp2-Ras-Erk signaling, heterogenous hepatocytes form clusters that manage to divide during mouse liver regeneration. These hepatocytes...

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Bibliographic Details
Main Authors: Kota Kaneko, Yan Liang, Qing Liu, Shuo Zhang, Alexander Scheiter, Dan Song, Gen-Sheng Feng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
Liver regeneration
Shp2/Ptpn11
CD133
vesicle trafficking
intercellular communication
drug resistance
Online Access:https://elifesciences.org/articles/86824

Internet

https://elifesciences.org/articles/86824

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