Aryl Hydrocarbon Receptor Activation by Benzo[<i>a</i>]pyrene Prevents Development of Septic Shock and Fatal Outcome in a Mouse Model of Systemic <i>Salmonella enterica</i> Infection

Aryl Hydrocarbon Receptor Activation by Benzo[<i>a</i>]pyrene Prevents Development of Septic Shock and Fatal Outcome in a Mouse Model of Systemic <i>Salmonella enterica</i> Infection

This study focused on immunomodulatory effects of aryl hydrocarbon receptor (AhR) activation through benzo[<i>a</i>]pyrene (BaP) during systemic bacterial infection. Using a well-established mouse model of systemic <i>Salmonella enterica</i> (S.E.) infection, we studied the i...

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Bibliographic Details
Main Authors: Christiane Fueldner, Sina Riemschneider, Janine Haupt, Harald Jungnickel, Felix Schulze, Katharina Zoldan, Charlotte Esser, Sunna Hauschildt, Jens Knauer, Andreas Luch, Stefan Kalkhof, Jörg Lehmann
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
aryl hydrocarbon receptor (AhR)
benzo[<i>a</i>]pyrene (BaP)
immunomodulation
interferon-γ
interleukin (IL)-12
IL-10
Online Access:https://www.mdpi.com/2073-4409/11/4/737

Internet

https://www.mdpi.com/2073-4409/11/4/737

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