A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

A qualitative transcriptional signature for the histological reclassification of lung squamous cell carcinomas and adenocarcinomas

Abstract Background Targeted therapy for non-small cell lung cancer is histology dependent. However, histological classification by routine pathological assessment with hematoxylin-eosin staining and immunostaining for poorly differentiated tumors, particularly those from small biopsies, is still ch...

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Bibliographic Details
Main Authors: Xin Li, Gengen Shi, Qingsong Chu, Wenbin Jiang, Yixin Liu, Sainan Zhang, Zheyang Zhang, Zixin Wei, Fei He, Zheng Guo, Lishuang Qi
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Genomics
Subjects:
Non-small cell lung cancer
Histological subtype
Pathological assessment
Relative gene expression orderings
Qualitative transcriptional signature
Online Access:http://link.springer.com/article/10.1186/s12864-019-6086-2

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http://link.springer.com/article/10.1186/s12864-019-6086-2

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