Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells

Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells

The aim of this study was to investigate the C-terminal cleavage of (pyr)-apelin-13 in human endothelial cells with respect to the role and subcellular location of prolyl carboxypeptidase (PRCP). Human umbilical vein and aortic endothelial cells, pre-treated with prolyl carboxypeptidase-inhibitor co...

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Bibliographic Details
Main Authors: Emilie De Hert, An Bracke, Isabel Pintelon, Eline Janssens, Anne-Marie Lambeir, Pieter Van Der Veken, Ingrid De Meester
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
angiotensin converting enzyme 2
human endothelial cells
prolyl carboxypeptidase
(pyr)-apelin-13
Online Access:https://www.mdpi.com/1422-0067/22/13/6698

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https://www.mdpi.com/1422-0067/22/13/6698

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