Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors

Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors

Abstract Background Malignant tumor is usually associated with epigenetic dysregulation, such as overexpression of histone deacetylase (HDAC), thus HDAC has emerged as a therapeutic target for cancer. Histone deacetylase inhibitor has been approved for clinical use to treat hematological cancers. Ho...

Full description

Bibliographic Details
Main Authors: Huan Li, Songpei Li, Yinshan Lin, Sheng Chen, Langyu Yang, Xin Huang, Hao Wang, Xiyong Yu, Lingmin Zhang
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Nanobiotechnology
Subjects:
Artificial exosomes
Upconversion nanoparticles
Epigenetic inhibition
M1 macrophages
Spatiotemporal-resolved delivery
Online Access:https://doi.org/10.1186/s12951-021-01107-9

Internet

https://doi.org/10.1186/s12951-021-01107-9

Similar Items