Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis

Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis

BackgroundUlcerative colitis (UC) is a lifelong inflammatory disease affecting the rectum and colon with numerous treatment options that require an individualized treatment plan. Histone modifications regulate chromosome structure and gene expression, resulting in effects on inflammatory and immune...

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Bibliographic Details
Main Authors: Shuyu Ye, Yongqing Lyu, Libin Chen, Yiwei Wang, Yue He, Quansi Li, Li Tian, Fen Liu, Xiaoyan Wang, Feiyan Ai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
histone modification
ulcerative colitis
molecular inflammatory predictive model
infliximab response
CAMK2D
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282136/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282136/full

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