d-Ribose as a Contributor to Glycated Haemoglobin
Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c. Using mass spectrometry, we detected glycation of haemoglobin with d-ribose produces 10 carboxylmethyllysines (CMLs). The first-order...
| Prif Awduron: | , , , , , , , , |
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| Fformat: | Erthygl |
| Iaith: | English |
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Elsevier
2017-11-01
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| Cyfres: | EBioMedicine |
| Pynciau: | |
| Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S2352396417303936 |