A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.

The red flour beetle Tribolium castaneum is a common insect pest and has been established as a model beetle to study insect development and immunity. This study demonstrates that defensin 1 from T. castaneum displays in vitro and in vivo antimicrobial activity against drug resistant Staphylococcus a...

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Bibliographic Details
Main Authors: Rajmohan Rajamuthiah, Elamparithi Jayamani, Annie L Conery, Beth Burgwyn Fuchs, Wooseong Kim, Tatiana Johnston, Andreas Vilcinskas, Frederick M Ausubel, Eleftherios Mylonakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4465704?pdf=render