JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis

JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis

Background/Aims Cholestatic liver diseases including primary biliary cholangitis (PBC) are associated with active hepatic fibrogenesis, which ultimately progresses to cirrhosis. Activated hepatic stellate cells (HSCs) are the main fibrogenic effectors in response to cholangiocyte damage. JCAD regula...

Full description

Bibliographic Details
Main Authors: Li Xie, Hui Chen, Li Zhang, Yue Ma, Yuan Zhou, Yong-Yu Yang, Chang Liu, Yu-Li Wang, Ya-Jun Yan, Jia Ding, Xiao Teng, Qiang Yang, Xiu-Ping Liu, Jian Wu
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2024-04-01
Series:Clinical and Molecular Hepatology
Subjects:
primary biliary cholangitis
cholestasis
hepatic stellate cells
jcad
hippo-yap signaling
Online Access:http://e-cmh.org/upload/pdf/cmh-2023-0506.pdf

Internet

http://e-cmh.org/upload/pdf/cmh-2023-0506.pdf

Similar Items