SMOC2 plays a role in heart failure via regulating TGF-β1/Smad3 pathway-mediated autophagy

Heart failure (HF) is a major global cause of morbidity and mortality. This study aimed to elucidate the role of secreted protein acidic and rich in cysteine-related modular calcium-binding protein 2 (SMOC2) in HF development and its underlying mechanism. Using a rat HF model, SMOC2 expression was e...

Full description

Bibliographic Details
Main Authors: Ren Yu, Wu Yun, He Wenshuai, Tian Yingjie, Zhao Xingsheng
Format: Article
Language:English
Published: De Gruyter 2023-07-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0752