Epigenetic age acceleration mediates the association between smoking and diabetes-related outcomes

Abstract Background Smoking can lead to the deterioration of lung function and susceptibility to diabetes. Recently, smoking was found to induce DNA methylation (DNAm) changes in some cytosine-phosphate-guanine sites (CpGs). As linear combinations of DNAm levels of aging-related CpGs, five measures...

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Bibliographic Details
Main Authors: Xue-Yong Chang, Wan-Yu Lin
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Clinical Epigenetics
Subjects:
Online Access:https://doi.org/10.1186/s13148-023-01512-x