Amnion and chorion matrix maintain hMSC osteogenic response and enhance immunomodulatory and angiogenic potential in a mineralized collagen scaffold

Amnion and chorion matrix maintain hMSC osteogenic response and enhance immunomodulatory and angiogenic potential in a mineralized collagen scaffold

Craniomaxillofacial (CMF) bone injuries present a major surgical challenge and cannot heal naturally due to their large size and complex topography. We are developing a mineralized collagen scaffold that mimics extracellular matrix (ECM) features of bone. These scaffolds induce in vitro human mesenc...

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Bibliographic Details
Main Authors: Vasiliki Kolliopoulos, Marley J. Dewey, Maxwell Polanek, Hui Xu, Brendan A. C. Harley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
craniomaxillofacial defects
bone regeneration
amnion membrane
chorion membrane
collagen scaffold
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1034701/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1034701/full

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