Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving fecal microbiome metabolism and enhancing the colonic barrier

Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving fecal microbiome metabolism and enhancing the colonic barrier

Osteoarthritis (OA) causes intestinal damage. The protective effect of probiotics on the intestine is indeed effective; however, the mechanism of protection against intestinal damage in OA is not clear. In this study, we used meniscal/ligamentous injury (MLI) to mimic OA in rats and explored the col...

Full description

Bibliographic Details
Main Authors: Jilang Tang, Xiaopeng Song, Mingchao Zhao, Hong Chen, Yingying Wang, Binger Zhao, Shiming Yu, Tianwen Ma, Li Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
osteoarthritic
Bacillus subtilis and Enterococcus faecium
inflammatory response
oxidative stress
fecal flora
untarget metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1005842/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1005842/full

Similar Items