Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis

Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis

Tumor cells can evade attack by phagocytes by upregulating the self-marker CD47. The mechanisms underlying tumor CD47 upregulation, however, remain unclear. Here, we report that human lung adenocarcinoma CD47 is upregulated by interferon-γ (IFN-γ), the level in the tumor microenvironment of which is...

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Bibliographic Details
Main Authors: Shuang Qu, Zichen Jiao, Geng Lu, Jiahan Xu, Bing Yao, Ting Wang, Jun Wang, Yongzhong Yao, Xin Yan, Tao Wang, Hongwei Liang, Ke Zen
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
lung adenocarcinoma
CD47
IFN-γ
metastasis
IRF1
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000638

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http://www.sciencedirect.com/science/article/pii/S2372770522000638

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