Estimating dose painting effects in radiotherapy: a mathematical model.

Tumor heterogeneity is widely considered to be a determinant factor in tumor progression and in particular in its recurrence after therapy. Unfortunately, current medical techniques are unable to deduce clinically relevant information about tumor heterogeneity by means of non-invasive methods. As a...

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Bibliographic Details
Main Authors: Juan Carlos López Alfonso, Nick Jagiella, Luis Núñez, Miguel A Herrero, Dirk Drasdo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3935877?pdf=render