Analysis of cyclophosphamide induced ovarian insufficiency and differentially expressed genes in rats

Objective To establish a stable cyclophosphamide(CTX) induced ovarian insufficiency rat model and to explore the mechanisms. Methods The survival curve of rats after intraperitoneal injection of different dosage of CTX was drawn and the optimal dose was determined. Sex hormone level, estrous cycle a...

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Bibliographic Details
Main Author: ZHANG Yu-lin, ZOU Heng, ZHANG Chan-yu
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-08-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-8-1243.pdf