Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice

Activated microglia have been associated with neurodegeneration in patients and in animal models of Temporal Lobe Epilepsy (TLE), however their precise functions as neurotoxic or neuroprotective is a topic of significant investigation. To explore this, we examined the effects of pilocarpine-induced...

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Bibliografiska uppgifter
Huvudupphovsmän: Martine M. Mirrione, Dorothy K. Konomos, Iordanis Gravanis, Stephen L. Dewey, Adriano Aguzzi, Frank L. Heppner, Stella E. Tsirka
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2010-07-01
Serie:Neurobiology of Disease
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Länkar:http://www.sciencedirect.com/science/article/pii/S0969996110000987