Characterization of three predicted zinc exporters in Brucella ovis identifies ZntR-ZntA as a powerful zinc and cadmium efflux system not required for virulence and unveils pathogenic Brucellae heterogeneity in zinc homeostasis

Characterization of three predicted zinc exporters in Brucella ovis identifies ZntR-ZntA as a powerful zinc and cadmium efflux system not required for virulence and unveils pathogenic Brucellae heterogeneity in zinc homeostasis

Brucella ovis causes non-zoonotic ovine brucellosis of worldwide distribution and is responsible for important economic losses mainly derived from male genital lesions and reproductive fails. Studies about the virulence mechanisms of this rough species (lacking lipopolysaccharide O-chains) are under...

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Bibliographic Details
Main Authors: Beatriz Tartilán-Choya, Carmen Tejedor, Raquel Conde-Álvarez, Pilar María Muñoz, Nieves Vizcaíno
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Veterinary Science
Subjects:
Brucella ovis
zinc
cadmium
cobalt
ZntA
ZntR
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1323500/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1323500/full

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