Effect of APOE ε4 allele on survival and fertility in an adverse environment.

Effect of APOE ε4 allele on survival and fertility in an adverse environment.

The apolipoprotein-ε4 allele (APOE-ε4) is strongly associated with detrimental outcomes in affluent populations including atherosclerotic disease, Alzheimer's disease, and reduced lifespan. Despite these detrimental outcomes, population frequencies of APOE-ε4 are high. We hypothesize that the h...

Full description

Bibliographic Details
Main Authors: Eric van Exel, Jacob J E Koopman, David van Bodegom, Johannes J Meij, Peter de Knijff, Juventus B Ziem, Caleb E Finch, Rudi G J Westendorp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5500260?pdf=render

Internet

http://europepmc.org/articles/PMC5500260?pdf=render

Similar Items