Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes

Human Herpesvirus 6B (HHV-6) can cause fever, diarrhea and roseola rash. Here the authors present a cryoEM approach to image crude, minimally purified virus samples and employ it to determine the atomic structures of HHV-6B capsid and capsid-associated tegument protein complexes.

Bibliographic Details
Main Authors: Yibo Zhang, Wei Liu, Zihang Li, Vinay Kumar, Ana L. Alvarez-Cabrera, Emily C. Leibovitch, Yanxiang Cui, Ye Mei, Guo-Qiang Bi, Steve Jacobson, Z. Hong Zhou
Format: Article
Language:English
Published: Nature Portfolio 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13064-x