Pharmacogenetic Analysis of Voriconazole Treatment in Children

Pharmacogenetic Analysis of Voriconazole Treatment in Children

Voriconazole is among the first-line antifungal drugs to treat invasive fungal infections in children and known for its pronounced inter- and intraindividual pharmacokinetic variability. Polymorphisms in genes involved in the metabolism and transport of voriconazole are thought to influence serum co...

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Bibliographic Details
Main Authors: Romy Tilen, Paolo Paioni, Aljoscha N. Goetschi, Roland Goers, Isabell Seibert, Daniel Müller, Julia A. Bielicki, Christoph Berger, Stefanie D. Krämer, Henriette E. Meyer zu Schwabedissen
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
children
pediatric pharmacology
voriconazole
therapeutic drug monitoring
pharmacogenetics
non-linear mixed effects modelling
Online Access:https://www.mdpi.com/1999-4923/14/6/1289

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https://www.mdpi.com/1999-4923/14/6/1289

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