Pharmacogenetic Analysis of Voriconazole Treatment in Children

Pharmacogenetic Analysis of Voriconazole Treatment in Children

Voriconazole is among the first-line antifungal drugs to treat invasive fungal infections in children and known for its pronounced inter- and intraindividual pharmacokinetic variability. Polymorphisms in genes involved in the metabolism and transport of voriconazole are thought to influence serum co...

Full description

Bibliographic Details
Main Authors:	Romy Tilen, Paolo Paioni, Aljoscha N. Goetschi, Roland Goers, Isabell Seibert, Daniel Müller, Julia A. Bielicki, Christoph Berger, Stefanie D. Krämer, Henriette E. Meyer zu Schwabedissen
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Series:	Pharmaceutics
Subjects:	children pediatric pharmacology voriconazole therapeutic drug monitoring pharmacogenetics non-linear mixed effects modelling
Online Access:	https://www.mdpi.com/1999-4923/14/6/1289

Similar Items

Principles of pharmacogenetics and pharmacogenomics /
by: Altman, Russ B. 205766, et al.
Published: (2012)

Pharmacogenetics in Pharmaceutical Care—Piloting an Application-Oriented Blended Learning Concept
by: Céline K. Stäuble, et al.
Published: (2021-09-01)

Treatment of invasive fungal infections: stability of voriconazole infusion solutions in PVC bags
by: Andréa I.H. Adams, et al.

Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
by: Irene García-García, et al.
Published: (2021-10-01)

To compare the safety and efficacy of intrastromal voriconazole alone and in combination with intracameral voriconazole in intractable cases of fungal keratitis
by: Monika Dahiya, et al.
Published: (2023-08-01)

Successful treatment of Chrysosporium keratitis with voriconazole
by: Thanathanee O, et al.
Published: (2017-03-01)

Uso de voriconazol en el período neonatal. Reporte de dos casos = Voriconazole use during the neonatal period. Report of two cases
by: Carvajal Kalil, Luis Fernando, et al.
Published: (2011-06-01)

Voriconazole-Induced Diffuse Periostitis
by: Simona Stefan, MD, et al.
Published: (2022-09-01)

Inflammation Affects Liver Function and the Metabolism of Voriconazole to Voriconazole-N-Oxide in Adult and Elderly Patients
by: Zaiming Liang, et al.
Published: (2022-04-01)

Voriconazole-induced periostitis post lung transplantation
by: Orla M. Murray, Bsc, et al.
Published: (2022-05-01)

Verapamil Inhibits Aspergillus Biofilm, but Antagonizes Voriconazole
by: Hasan Nazik, et al.
Published: (2017-09-01)

Pharmacogenetic-Guided Antidepressant Selection as an Opportunity for Interprofessional Collaboration: A Case Report
by: Céline K. Stäuble, et al.
Published: (2021-07-01)

Voriconazole-induced periostitis
by: D.C. Fernández Ávila, et al.
Published: (2021-04-01)

Pseudoporphyria Induced by Voriconazole in a 10-year-old Boy: A Case Report and Review of the Literature
by: Francesca Caroppo, et al.
Published: (2023-05-01)

Recurrent Acremonium infection in a kidney transplant patient treated with voriconazole: a case report Infecção recidivante por Acremonium em paciente transplantado renal tratado com voriconazol: relato de caso
by: Felipe Francisco Tuon, et al.
Published: (2010-08-01)

Application of pharmacogenetics in oncology
by: Nelly N. Miteva-Marcheva, et al.
Published: (2020-08-01)

An appraisal of antifungal impacts of nano-liposome containing voriconazole on voriconazole-resistant Aspergillus flavus isolates as a groundbreaking drug delivery system
by: Parviz Hassanpour, et al.
Published: (2020-03-01)

Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients
by: Lin Cheng, et al.
Published: (2023-02-01)

RP-HPTLC method for determination of Voriconazole in bulk and in cream formulation
by: Manali W. Jain, et al.
Published: (2017-02-01)

Hallucination in kidney transplant recipient: A rare complication of voriconazole
by: Manmeet Singh Jhawar, et al.
Published: (2017-01-01)

Systematic Evaluation of Voriconazole Pharmacokinetic Models without Pharmacogenetic Information for Bayesian Forecasting in Critically Ill Patients
by: Simon Kallee, et al.
Published: (2022-09-01)

Bronchoscopic Voriconazole Instillation in Pulmonary Aspergilloma: A Single Center Experience
by: Prajowl Shrestha, et al.
Published: (2019-06-01)

Natamycin versus voriconazole for fungal keratitis
by: José Retamal, et al.
Published: (2018-12-01)

Pharmacogenetic Analysis Enables Optimization of Pain Therapy: A Case Report of Ineffective Oxycodone Therapy
by: Florine M. Wiss, et al.
Published: (2023-05-01)

Colon Cancer Pharmacogenetics: A Narrative Review
by: Álvaro Esteban Alfaro Alfaro, et al.
Published: (2022-08-01)

Intravitreal Voriconazole for Treatment of Bilateral Endogenous Candida Chorioretinitis
by: Ha Eun Sim, et al.
Published: (2020-08-01)

Determination of voriconazole and its N-oxide in human plasma by LC-MS/MS and its clinical application
by: XIANG Rongfeng, et al.
Published: (2019-08-01)

Pharmacogenetics from ethno-cultural perspectives
by: Chee Ng, et al.
Published: (2010-12-01)

Establishment of a Pharmacogenetics Service Focused on Optimizing Existing Pharmacogenetic Testing at a Large Academic Health Center
by: Amy L. Pasternak, et al.
Published: (2020-10-01)

New bearings in pharmacotherapeutic strategies: Pharmacogenetics and gene therapy
by: Grbović Leposava, et al.
Published: (2007-01-01)

Neurological adverse events to voriconazole: evidence for therapeutic drug monitoring
by: Swiss Medical Weekly
Published: (2006-11-01)

A case presentation of Voriconazole therapy in a brochopulmonary dysplasia
by: Elaheh Amini, et al.
Published: (2015-03-01)

The combined utilization of Chlorhexidine and Voriconazole or Natamycin to combat Fusarium infections
by: Tao Jiang, et al.
Published: (2020-09-01)

The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro
by: Xu RA, et al.
Published: (2018-11-01)

Pharmacogenetic Testing in Acute and Chronic Pain: A Preliminary Study
by: Lorenzo Panella, et al.
Published: (2019-05-01)

Comparative study of prophylaxis with high and low doses of voriconazole in children with malignancy
by: Sviatlana Kandaurava, et al.
Published: (2020-12-01)

Rechallenge of voriconazole successfully tolerated after hepatic toxicity
by: O. Narumoto, et al.
Published: (2020-01-01)

Evaluation of Plasma Concentration and Hepatotoxicity of Voriconazole in Pediatric Patients following Hematopoietic Stem Cell Transplantation
by: Hamidreza Taghvaye Masoumi, et al.
Published: (2017-09-01)

Is Pharmacogenetic Panel Testing Applicable to Low-Dose Methotrexate in Rheumatoid Arthritis? – A Case Report
by: Jeiziner C, et al.
Published: (2022-05-01)

Pharmacokinetics and safety of two Voriconazole formulations after intravenous infusion in two doses in healthy Chinese subjects
by: Xin Li, et al.
Published: (2023-03-01)