Total Synthesis of Hemerocallisamine I Paved by Gram-Scale Synthesis of (2<i>S</i>,4<i>S</i>)-4-Hydroxyglutamic Acid Lactone
Total synthesis of the 2-formylpyrrole alkaloid hemerocallisamine I is presented, both in racemic and enantiopure form. Our synthetic strategy involves (2<i>S</i>,4<i>S</i>)-4-hydroxyglutamic acid lactone as the key intermediate. Starting from an achiral substrate, the target...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/5/2177 |