Controlling Pericellular Oxygen Tension in Cell Culture Reveals Distinct Breast Cancer Responses to Low Oxygen Tensions

Controlling Pericellular Oxygen Tension in Cell Culture Reveals Distinct Breast Cancer Responses to Low Oxygen Tensions

Abstract In oxygen (O2)‐controlled cell culture, an indispensable tool in biological research, it is presumed that the incubator setpoint equals the O2 tension experienced by cells (i.e., pericellular O2). However, it is discovered that physioxic (5% O2) and hypoxic (1% O2) setpoints regularly induc...

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Détails bibliographiques
Auteurs principaux: Zachary J. Rogers, Thibault Colombani, Saad Khan, Khushbu Bhatt, Alexandra Nukovic, Guanyu Zhou, Benjamin M. Woolston, Cormac T. Taylor, Daniele M. Gilkes, Nikolai Slavov, Sidi A. Bencherif
Format: Article
Langue:English
Publié: Wiley 2024-08-01
Collection:Advanced Science
Sujets:
anoxia
breast cancer
cancer metabolism
cell culture
hypoxia
hypoxia‐inducible factors
Accès en ligne:https://doi.org/10.1002/advs.202402557

Internet

https://doi.org/10.1002/advs.202402557

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