Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure

Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research. Here we used CD4+ lymphocyte depletions to dissect the impact of cellular immunity on humoral responses during a tert...

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Bibliographic Details
Main Authors: Nicole Marzan-Rivera, Crisanta Serrano-Collazo, Lorna Cruz, Petraleigh Pantoja, Alexandra Ortiz-Rosa, Teresa Arana, Melween I. Martinez, Armando G. Burgos, Chiara Roman, Loyda B. Mendez, Elizabeth Geerling, Amelia K. Pinto, James D. Brien, Carlos A. Sariol
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010367