Genomics of Aminoglycoside Resistance in Pseudomonas aeruginosa Bloodstream Infections at a United States Academic Hospital

Genomics of Aminoglycoside Resistance in Pseudomonas aeruginosa Bloodstream Infections at a United States Academic Hospital

ABSTRACT Pseudomonas aeruginosa frequently becomes resistant to aminoglycosides by the acquisition of aminoglycoside modifying enzyme (AME) genes and the occurrence of mutations in the mexZ, fusA1, parRS, and armZ genes. We examined resistance to aminoglycosides in a collection of 227 P. aeruginosa...

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Bibliographic Details
Main Authors: Giancarlo Atassi, Rachel Medernach, Marc Scheetz, Sophia Nozick, Nathaniel J. Rhodes, Megan Murphy-Belcaster, Katherine R. Murphy, Arghavan Alisoltani, Egon A. Ozer, Alan R. Hauser
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
aminoglycosides
aminoglycoside modifying enzymes
resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05087-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05087-22

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