Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation.
Pericentrin is a conserved centrosomal protein whose dysfunction has been linked to several human diseases. It has been implicated in many aspects of centrosome and cilia function, but its precise role is unclear. Here, we examine Drosophila Pericentrin-like-protein (PLP) function in vivo in tissues...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5823460?pdf=render |