In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome

In Situ Peroxidase Labeling Followed by Mass-Spectrometry Reveals TIA1 Interactome

TIA1 is a broadly expressed DNA/RNA binding protein that regulates multiple aspects of RNA metabolism. It is best known for its role in stress granule assembly during the cellular stress response. Three RNA recognition motifs mediate TIA1 functions along with a prion-like domain that supports multiv...

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Bibliographic Details
Main Authors: Olga Gourdomichali, Katerina Zonke, Fedon-Giasin Kattan, Manousos Makridakis, Georgia Kontostathi, Antonia Vlahou, Epaminondas Doxakis
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biology
Subjects:
TIA1
APEX2
proximity labeling
proteomics
LC-MS/MS
RNA binding proteins
Online Access:https://www.mdpi.com/2079-7737/11/2/287

Internet

https://www.mdpi.com/2079-7737/11/2/287

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