Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression

IntroductionChronic spinal compression is a common complication of spinal cord injury (SCI), which can lead to spinal stenosis or herniated discs. The ensuing neuropathic pain is often associated with the activation of microglia. In this investigation, our objective was to explore whether modifying...

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Bibliographic Details
Main Authors: Quan Li, Zongde Yang, Kun Wang, Zhi Chen, Hongxing Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1191188/full