High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control
In human cell lines, DNA replication initiates primarily from a set of genomic loci shared across single cells, which fire according to a predictable but not strictly deterministic order.
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-30212-y |