High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control

In human cell lines, DNA replication initiates primarily from a set of genomic loci shared across single cells, which fire according to a predictable but not strictly deterministic order.

Bibliographic Details
Main Authors: Dashiell J. Massey, Amnon Koren
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30212-y