Translation-Associated Mutational U-Pressure in the First ORF of SARS-CoV-2 and Other Coronaviruses

Translation-Associated Mutational U-Pressure in the First ORF of SARS-CoV-2 and Other Coronaviruses

Within 4 months of the ongoing COVID-19 pandemic caused by SARS-CoV-2, more than 250 nucleotide mutations have been detected in ORF1ab of the virus isolated from infected persons from different parts of the globe. These observations open up an obvious question about the rate and direction of mutatio...

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Bibliographic Details
Main Authors: Vladislav Victorovich Khrustalev, Rajanish Giri, Tatyana Aleksandrovna Khrustaleva, Shivani Krishna Kapuganti, Aleksander Nicolaevich Stojarov, Victor Vitoldovich Poboinev
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
COVID-19
SARS
MERS
mutational pressure
cytosine deamination
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.559165/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.559165/full

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