Akt isoforms differentially provide for chemoresistance in prostate cancer
Objective: Early prostate cancer micrometastatic foci undergo a mesenchymal to epithelial reverting transition, not only aiding seeding and colonization, but also rendering the tumor cells generally chemoresistant. We previously found that upregulated E-cadherin in the epithelial micrometastases act...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
China Anti-Cancer Association
2022-05-01
|
Series: | Cancer Biology & Medicine |
Subjects: | |
Online Access: | https://www.cancerbiomed.org/content/19/5/635 |