Akt isoforms differentially provide for chemoresistance in prostate cancer

Objective: Early prostate cancer micrometastatic foci undergo a mesenchymal to epithelial reverting transition, not only aiding seeding and colonization, but also rendering the tumor cells generally chemoresistant. We previously found that upregulated E-cadherin in the epithelial micrometastases act...

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Bibliographic Details
Main Authors: Bo Ma, Hanshuang Shao, Xia Jiang, Zhou Wang, Chuanyue (Cary) Wu, Diana Whaley, Alan Wells
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-05-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:https://www.cancerbiomed.org/content/19/5/635