Anoxia-induced hippocampal LTP is regeneratively produced by glutamate and nitric oxide from the neuro-glial-endothelial axis

Summary: Transient anoxia causes amnesia and neuronal death. This is attributed to enhanced glutamate release and modeled as anoxia-induced long-term potentiation (aLTP). aLTP is mediated by glutamate receptors and nitric oxide (·NO) and occludes stimulation-induced LTP. We identified a signaling ca...

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Bibliographic Details
Main Authors: Han-Ying Wang, Hiroshi Takagi, Patrick N. Stoney, Anai Echeverria, Bernd Kuhn, Kuei-Sen Hsu, Tomoyuki Takahashi
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007363