Long‐term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice

Abstract Background The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has s...

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Bibliographic Details
Main Authors: Anna Carolina Zaia Rodrigues, María Laura Messi, Zhong‐Min Wang, Henry Jacob Bonilla, Willard M. Freeman, Osvaldo Delbono
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.12790