Hepatic Expression of the Na<sup>+</sup>-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

Hepatic Expression of the Na<sup>+</sup>-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

The hepatic Na<sup>+</sup>-taurocholate cotransporting polypeptide NTCP/<i>SLC10A1</i> is important for the uptake of bile salts and selected drugs. Its inhibition results in increased systemic bile salt concentrations. NTCP is also the entry receptor for the hepatitis B/D vi...

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Bibliographic Details
Main Authors: Roman Tremmel, Anne T. Nies, Barbara A. C. van Eijck, Niklas Handin, Mathias Haag, Stefan Winter, Florian A. Büttner, Charlotte Kölz, Franziska Klein, Pascale Mazzola, Ute Hofmann, Kathrin Klein, Per Hoffmann, Markus M. Nöthen, Fabienne Z. Gaugaz, Per Artursson, Matthias Schwab, Elke Schaeffeler
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>SLC10A1</i>
NTCP
genetic variants
epigenetics
metabolomics
HBV/HDV infection
Online Access:https://www.mdpi.com/1422-0067/23/13/7468

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https://www.mdpi.com/1422-0067/23/13/7468

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