Toll-like receptors 2 and 4 differentially regulate the self-renewal and differentiation of spinal cord neural precursor cells

Abstract Background Toll-like receptors (TLRs) represent critical effectors in the host defense response against various pathogens; however, their known function during development has also highlighted a potential role in cell fate determination and neural differentiation. While glial cells and neur...

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Bibliographic Details
Main Authors: Marina Sanchez-Petidier, Consuelo Guerri, Victoria Moreno-Manzano
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-022-02798-z