A plant protein signal sequence improved humoral immune response to HPV prophylactic and therapeutic DNA vaccines

A plant protein signal sequence improved humoral immune response to HPV prophylactic and therapeutic DNA vaccines

Signal sequences (ss) play a critical role in the sorting of nascent secretory and membrane proteins. This function has been conserved from bacteria through eukaryotes, although ss appear diverse in length and amino acid composition. Sorting of proteins is also critical to instruct antigens for a pr...

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Bibliographic Details
Main Authors: Silvia Massa, Francesca Paolini, Gianfranca Curzio, Marcelo Nazario Cordeiro, Elena Illiano, Olivia Costantina Demurtas, Rosella Franconi, Aldo Venuti
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
humoral immune response
hpv
infectious diseases
plant signal sequences
vaccines
Online Access:http://dx.doi.org/10.1080/21645515.2017.1264766

Internet

http://dx.doi.org/10.1080/21645515.2017.1264766

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