3D RNA-scaffolded wireframe origami

Hybrid nucleic acid origami has potential for biomedical delivery of mRNA and fabrication of artificial ribozymes. Here, the authors use chemical footprinting and cryo-electron microscopy to reveal insights into nucleic acid origami used to fold messenger and ribosomal RNA into 3D polyhedral structu...

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Bibliographic Details
Main Authors: Molly F. Parsons, Matthew F. Allan, Shanshan Li, Tyson R. Shepherd, Sakul Ratanalert, Kaiming Zhang, Krista M. Pullen, Wah Chiu, Silvi Rouskin, Mark Bathe
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36156-1