Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer

<p>Abstract</p> <p>Background</p> <p>Eukaryotic initiation factor 4E (eIF4E) is elevated in many cancers and is a prognostic indicator in breast cancer. Many pro-tumorigenic proteins are selectively translated via eIF4E, including c-Myc, cyclin D1, ornithine decarboxyla...

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Bibliographic Details
Main Authors: Clifford John, Mathis J Michael, Chu Quyen, Cardelli James, Unger Marcia, Adegboyega Patrick, Lowery-Nordberg Mary, Shi Runhua, Meschonat Carol, Smith Mark, Tubbs Jesse, Krishnan Prasad, Kleiner Heather E, De Benedetti Arrigo, Li Benjamin DL
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/28/1/5