Next generation proteomics with drug sensitivity screening identifies sub-clones informing therapeutic and drug development strategies for multiple myeloma patients

Abstract With the introduction of novel therapeutic agents, survival in Multiple Myeloma (MM) has increased in recent years. However, drug-resistant clones inevitably arise and lead to disease progression and death. The current International Myeloma Working Group response criteria are broad and make...

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Bibliographic Details
Main Authors: Ciara Tierney, Despina Bazou, Muntasir M. Majumder, Pekka Anttila, Raija Silvennoinen, Caroline A. Heckman, Paul Dowling, Peter O’Gorman
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90149-y