Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation.

Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation.

Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...

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Bibliographic Details
Main Authors: Jun-Ha Hwang, Mi Ran Byun, A Rum Kim, Kyung Min Kim, Hang Jun Cho, Yo Han Lee, Juwon Kim, Mi Gyeong Jeong, Eun Sook Hwang, Jeong-Ho Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4532446?pdf=render

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http://europepmc.org/articles/PMC4532446?pdf=render

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