Lambda CI Binding to Related Phage Operator Sequences Validates Alignment Algorithm and Highlights the Importance of Overlooked Bonds

Bacteriophage λ’s CI repressor protein controls a genetic switch between the virus’s lysogenic and lytic lifecycles, in part, by selectively binding to six different DNA sequences within the phage genome—collectively referred to as operator sites. However, the minimal level of information needed for...

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Bibliographic Details
Main Authors: Jacklin Sedhom, Lee A. Solomon
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/12/2221