Assessment of the In Vitro and In Vivo Antifungal Activity of NSC319726 against Candida auris

ABSTRACT Candida auris is an emerging yeast pathogen of candidemia with the ability to develop resistance to all current antifungal drug classes. Novel antifungal therapies against C. auris are warranted. NSC319726 is a thiosemicarbazone with an inhibitory effect on fungal ribosome biogenesis that h...

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Bibliographic Details
Main Authors: Jizhou Li, Alix T. Coste, Daniel Bachmann, Dominique Sanglard, Frederic Lamoth
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.01395-21