Photoactivatable CaMKII induces synaptic plasticity in single synapses

Optogenetic control of molecules is important in cell biology and neuroscience. Here, the authors describe an optogenetic tool to control the Ca²+/calmodulin-dependent protein kinase II and use it to control plasticity at the single synapse level.

Bibliographic Details
Main Authors: Akihiro C. E. Shibata, Hiromi H. Ueda, Kei Eto, Maki Onda, Aiko Sato, Tatsuko Ohba, Junichi Nabekura, Hideji Murakoshi
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21025-6