Photoactivatable CaMKII induces synaptic plasticity in single synapses
Optogenetic control of molecules is important in cell biology and neuroscience. Here, the authors describe an optogenetic tool to control the Ca²+/calmodulin-dependent protein kinase II and use it to control plasticity at the single synapse level.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21025-6 |
| _version_ | 1818432274903859200 |
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| author | Akihiro C. E. Shibata Hiromi H. Ueda Kei Eto Maki Onda Aiko Sato Tatsuko Ohba Junichi Nabekura Hideji Murakoshi |
| author_facet | Akihiro C. E. Shibata Hiromi H. Ueda Kei Eto Maki Onda Aiko Sato Tatsuko Ohba Junichi Nabekura Hideji Murakoshi |
| author_sort | Akihiro C. E. Shibata |
| collection | DOAJ |
| description | Optogenetic control of molecules is important in cell biology and neuroscience. Here, the authors describe an optogenetic tool to control the Ca²+/calmodulin-dependent protein kinase II and use it to control plasticity at the single synapse level. |
| first_indexed | 2024-12-14T16:02:36Z |
| format | Article |
| id | doaj.art-10956bdf444d4e04bb52e1f2f0632996 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T16:02:36Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-10956bdf444d4e04bb52e1f2f06329962022-12-21T22:55:09ZengNature PortfolioNature Communications2041-17232021-02-0112111510.1038/s41467-021-21025-6Photoactivatable CaMKII induces synaptic plasticity in single synapsesAkihiro C. E. Shibata0Hiromi H. Ueda1Kei Eto2Maki Onda3Aiko Sato4Tatsuko Ohba5Junichi Nabekura6Hideji Murakoshi7Supportive Center for Brain Research, National Institute for Physiological SciencesSupportive Center for Brain Research, National Institute for Physiological SciencesDepartment of Physiological Sciences, The Graduate University for Advanced StudiesSupportive Center for Brain Research, National Institute for Physiological SciencesSupportive Center for Brain Research, National Institute for Physiological SciencesDivision of Homeostatic Development, National Institute for Physiological SciencesDepartment of Physiological Sciences, The Graduate University for Advanced StudiesSupportive Center for Brain Research, National Institute for Physiological SciencesOptogenetic control of molecules is important in cell biology and neuroscience. Here, the authors describe an optogenetic tool to control the Ca²+/calmodulin-dependent protein kinase II and use it to control plasticity at the single synapse level.https://doi.org/10.1038/s41467-021-21025-6 |
| spellingShingle | Akihiro C. E. Shibata Hiromi H. Ueda Kei Eto Maki Onda Aiko Sato Tatsuko Ohba Junichi Nabekura Hideji Murakoshi Photoactivatable CaMKII induces synaptic plasticity in single synapses Nature Communications |
| title | Photoactivatable CaMKII induces synaptic plasticity in single synapses |
| title_full | Photoactivatable CaMKII induces synaptic plasticity in single synapses |
| title_fullStr | Photoactivatable CaMKII induces synaptic plasticity in single synapses |
| title_full_unstemmed | Photoactivatable CaMKII induces synaptic plasticity in single synapses |
| title_short | Photoactivatable CaMKII induces synaptic plasticity in single synapses |
| title_sort | photoactivatable camkii induces synaptic plasticity in single synapses |
| url | https://doi.org/10.1038/s41467-021-21025-6 |
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