Anti-Osteoporotic Effects of <i>n-trans</i>-Hibiscusamide and Its Derivative Alleviate Ovariectomy-Induced Bone Loss in Mice by Regulating RANKL-Induced Signaling

Anti-Osteoporotic Effects of <i>n-trans</i>-Hibiscusamide and Its Derivative Alleviate Ovariectomy-Induced Bone Loss in Mice by Regulating RANKL-Induced Signaling

Osteoporosis is characterized by the deterioration of bone structures and decreased bone mass, leading to an increased risk of fracture. Estrogen deficiency in postmenopausal women and aging are major factors of osteoporosis and are some of the reasons for reduced quality of life. In this study, we...

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Bibliographic Details
Main Authors: Hyung Jin Lim, Eun-Jae Park, Yeong-Seon Won, Seon Gyeong Bak, Sun Hee Cheong, Seung Woong Lee, Soyoung Lee, Seung-Jae Lee, Mun-Chual Rho
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
<i>n-trans</i>-hibiscusamide
4-<i>O</i>-(<i>E</i>)-feruloyl-<i>N-</i>(<i>E</i>)-hibiscusamide
osteoclastogenesis
OVX induced osteoporosis
Online Access:https://www.mdpi.com/1420-3049/26/22/6820

Internet

https://www.mdpi.com/1420-3049/26/22/6820

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