The evolution and mutational robustness of chromatin accessibility in Drosophila

The evolution and mutational robustness of chromatin accessibility in Drosophila

Abstract Background The evolution of genomic regulatory regions plays a critical role in shaping the diversity of life. While this process is primarily sequence-dependent, the enormous complexity of biological systems complicates the understanding of the factors underlying regulation and its evoluti...

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Bibliographic Details
Main Authors: Samuel Khodursky, Eric B. Zheng, Nicolas Svetec, Sylvia M. Durkin, Sigi Benjamin, Alice Gadau, Xia Wu, Li Zhao
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Genome Biology
Subjects:
Deep learning
Drosophila
ATAC-seq
Chromatin accessibility
In silico mutagenesis
Robustness
Online Access:https://doi.org/10.1186/s13059-023-03079-5

Internet

https://doi.org/10.1186/s13059-023-03079-5

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